New case study shows that supplementation with phytosterols saves healthcare costs
A recent case study published by Food Supplements Europe indicated that the use of food supplements with added phytosterols (i.e. plant stanols or sterols) could potentially reduce cardiovascular disease attributed healthcare costs among high risk populations in the EU. The potential savings were based on the cholesterol-lowering effect of phytosterols and the consequential reductions in CVD-attributed hospital utilization costs.
The calculations included adults age 55 and older with serum cholesterol levels above 6.2 mmol/L and an expected 24.3% risk of experiencing a costly cardiovascular disease attributed hospital event, and a daily intake of 1.7 g phytosterols from food supplements was expected to reduce serum LDL-cholesterol by 8.4% in this population.
The potential cost savings varied between countries but according to the report, on average €4.37 could be saved for every €1.00 spent on a phytosterol daily regimen. Moreover, an indication of the cost effectiveness of phytosterols in all 28 EU countries could be demonstrated. Thus, a targeted phytosterol regimen was recommended for high-risk individuals as a means to lower LDL-cholesterol and to consequently help control rising societal healthcare costs.
The case study was commissioned by Food Supplement Europe and conducted by Frost & Sullivan.
More information: http://www.foodsupplementseurope.org/value-of-supplementation/
New EAS Consensus Statement confirms the causal role of LDL in atherosclerotic cardiovascular disease
The European Atherosclerosis Society (EAS) recently published a new Consensus Statement1 which confirms the causal role of low-density lipoproteins (LDL) in the development of atherosclerotic cardiovascular disease (ASCVD).
The consensus statement is based on a meta-analysis of more than 200 prospective cohort studies, Mendelian randomization studies, and randomized controlled trials, including in total over 2 million participants, more than 20 million person-years of follow-up, and over 150 000 cardiovascular events. The main conclusion presented in the consensus statement is: “Consistent evidence from numerous and multiple different types of clinical and genetic studies unequivocally establishes that LDL causes ASCVD”.
The new consensus statement thus confirms that LDL is not only a biomarker, but a causal factor for ASCVD. It also states that the effect of LDL-C is cumulative, meaning that the higher the LDL-C is and the longer a person has elevated LDL-C, the higher is the risk of ASCVD. Thus, lowering LDL-cholesterol throughout the life through dietary and other lifestyle measures will be a major opportunity to reduce the lifetime risk of a cardiovascular event.
1. Ference B et al. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel. Eur Heart J 2017. doi:10.1093/eurheartj/ehx144.
New study: Benecol® Soft Chews effectively lower LDL-cholesterol
The cholesterol-lowering efficacy of plant stanol ester is well documented in over 70 published clinical trials with different study designs. A recently published study1 adds to this strong evidence-base as it confirms the LDL-cholesterol lowering efficacy of the new Benecol® Soft Chews. These food supplements with plant stanol ester are the latest addition to the Benecol® product range.
The subjects in the double-blind, randomized, and placebo-controlled study by Laitinen et al. used two soft chews twice a day with main meals, so they consumed altogether 4 pieces of the soft chew per day for four weeks.
The results showed that compared to a placebo food supplement, the food supplement with plant stanol ester (2 g/d plant stanols) reduced LDL cholesterol significantly by 7.6% (p=0.001). Almost four fifths (78%) of the study subjects considered the food supplement as easy to use, and 68% rated the taste as good or very good. No side effects were reported.
The new Benecol® Soft Chews with plant stanol ester provide an innovative new solution for serum cholesterol lowering. As the name of the product suggests, this food supplement is soft and easily chewable, and a convenient on-the-go solution for effective cholesterol-lowering.
Benecol Soft Chews Lemon & Lime are available in the Netherlands, Ireland, Belgium, Poland, and Finland, and via Raisio’s webstore.
1. Laitinen K, Gylling H, Kaipiainen L, Nissinen MJ, Simonen P. Cholesterol lowering efficacy of plant stanol ester in a new type of product matrix, a chewable dietary supplement. J Funct Foods 2017; 30: 119-124
Diet and lifestyle in focus at the 2016 EAS Congress in Innsbruck
Diet and lifestyle were among the hot topics at the 2016 EAS Congress in Innsbruck. The yearly congress of the European Atherosclerosis Society (EAS) gathered around 3,000 scientists and clinicians to Innsbruck to discuss the latest developments in the prevention and treatment of atherosclerotic vascular diseases.
The main message from many different educational sessions was that diet should be looked at as an entity, not as single nutrients. Saturated fats are also still in focus, however, and replacing them with unsaturated fats and whole grains has been shown to lower the risk of cardiovascular diseases. Furthermore, growing evidence shows that attention should paid to the intake of sugar because a high intake of sugar, especially added sugar from sugar sweetened beverages, is clearly associated with overweight, obesity, and cardiovascular diseases.
Educating patients about healthy dietary patterns was seen as a key. A healthy diet emphasizes the consumption of vegetables, fruits, berries, legumes, nuts and seeds, as well as whole grains, low-fat milk products, vegetable oils and fish. It encourages people to restrict the consumption of red and processed meats, refined grains, added sugars, salt and foods rich in saturated and trans fats. If additional LDL-cholesterol lowering measures are needed, foods with added plant stanols or sterols can well be considered as part of the management.
During the EAS Congress, a new version of the educational online tutorial, "Diet at the Heart of CVD Prevention", was published. The DietattheHeart 2.0 version has been updated and broadened to provide extensive information about the role of diet in the management of dyslipidemia. The tutorial has been developed in collaboration with leading experts, and it is endorsed by the EAS. Please visit www.dietattheheart.com whenever you want to refresh or test your knowledge about the current dietary guidelines concerning the management of dyslipidemia, or when you need printable materials for patient education.